Luer Locks disconnects are generally used in medical and industrial applications.  Compatible male and female Luer Locks twist together to make a airtight, pressure capable connection.

I use Luer Lock style connectors for a CO2 utility line for my draft system.  That allows me to quickly and easily switch between a number of CO2 utility attachments that I don’t use on a day to day basis.  The reason I chose Luer Locks is that they are generally inexpensive.  You could also use these as a primary disconnect for your CO2 system.

1/9 5 PM Central: These are on sale for just $7.99. Shipping is also free to many US addresses with Prime Membership [Try Prime for Free] or a qualifying order.  Prices and availability can change quickly.  Check product page for current info – More About Prices

30pcs Luer Lock Adapter, Clear Female Luer Lock 1/4 Luer Lock Connector Kit Luer Connector– affiliate link, note that multiple variations of this product may be available, as such a different version may appear at this link

Also Consider:

• MEETOOT 10pcs Female Luer Lock 1/4″ Polycarbonate Hose Barb Adapter for Laboratory Biochemical/Analytical Instruments, Food Machinery and Aquarium Equipment – affiliate link, note that multiple variations of this product may be available, as such a different version may appear at this link
• MEETOOT 10pcs Male Luer Lock 1/4″ PP Hose Barb Adapter for Laboratory Biochemical/Analytical Instruments, Food Machinery and Aquarium Equipment – affiliate link, note that multiple variations of this product may be available, as such a different version may appear at this link

MEETOOT 10pcs Male Luer Lock 1/4" PP Hose Barb Adapter for Laboratory Biochemical/Analytical Instruments, Food Machinery and Aquarium Equipment

$7.99

MEETOOT 10pcs Female Luer Lock 1/4" Polycarbonate Hose Barb Adapter for Laboratory Biochemical/Analytical Instruments, Food Machinery and Aquarium Equipment

$8.99

Related: Making a Utility CO2 Line using Luer Lock Disconnects

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Make sure the components you use are compatible and rated for your intended application.  Contact manufacturer with questions about suitability or a specific application.  Always read and follow manufacturer directions.